80 may refer to:
80 (number)
one of the years 80 BC, AD 80, 1980, 2080
B. B. King & Friends: 80, an album released in 2005
80 (Tolis Voskopoulos album), released in 1980
Audi 80, a precursor of the Audi A4 automobile
Boeing 80, a late-1920s Boeing aircraft
"80", a song by Green Day from their 1991 album Kerplunk!
80 Sappho, a main-belt asteroid