727 may refer to:
Boeing 727, an airliner
AD 727, a year
727 BC, a year
727 (number), a number
"727", a song by The Box Tops from the album Cry Like a Baby
7/27, a 2016 album by Fifth Harmony
Area code 727, for telephones in Pinellas County, Florida
USS Michigan (SSBN-727), a U.S. ballistic missile submarine
Jet 727, a bus service in Aberdeen, Scotland